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Knockdown of Glutamate Cysteine Ligase Catalytic Subunit by siRNA Causes the Gold Nanoparticles-Induced Cytotoxicity in Lung Cancer Cells
Gold nanoparticles (GNPs) have shown promising medical applications in cancer treatment involved in the regulation of intracellular redox balance. Previously, we have reported that GNPs can trigger apoptosis and necrosis in human lung cancer cells (A549) when L-buthionine-sulfoximine (BSO) was used...
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Veröffentlicht in: | PLoS One |
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Hauptverfasser: | , , |
Format: | Artigo |
Sprache: | Inglês |
Veröffentlicht: |
Public Library of Science
2015
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Schlagworte: | |
Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4366198/ https://ncbi.nlm.nih.gov/pubmed/25789740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118870 |
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