Cytoplasmic PELP1 and ERRgamma Protect Human Mammary Epithelial Cells from Tam-Induced Cell Death

Tamoxifen (Tam) is the only FDA-approved chemoprevention agent for pre-menopausal women at high risk for developing breast cancer. While Tam reduces a woman's risk of developing estrogen receptor positive (ER+) breast cancer, the molecular mechanisms associated with risk reduction are poorly un...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Girard, Brian J., Regan Anderson, Tarah M., Welch, Siya Lem, Nicely, Julie, Seewaldt, Victoria L., Ostrander, Julie H.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4366195/
https://ncbi.nlm.nih.gov/pubmed/25789479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121206
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