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Interferon alpha Induced Intrahepatic pSTAT1 Inversely Correlate with Serum HCV RNA Levels in Chronic HCV Infection

BACKGROUND: The Jak-STAT signaling of hepatitis C virus (HCV) infected hepatocyte is critical for the antiviral action of endogenously produced interferon (IFN) as well as exogenously administered interferon alpha (IFN-α). The activation of cellular Jak-STAT signaling by IFN-α results in the phospho...

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Publicado en:Exp Mol Pathol
Autores principales: Gunduz, Feyza, Mallikarjun, Chaithanya, Balart, Luis A, Dash, Srikanta
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365860/
https://ncbi.nlm.nih.gov/pubmed/24211829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yexmp.2013.10.016
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