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Dysregulated serum response factor triggers formation of hepatocellular carcinoma
The ubiquitously expressed transcriptional regulator serum response factor (SRF) is controlled by both Ras/MAPK (mitogen-activated protein kinase) and Rho/actin signaling pathways, which are frequently activated in hepatocellular carcinoma (HCC). We generated SRF-VP16(iHep) mice, which conditionally...
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| 出版年: | Hepatology |
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| 主要な著者: | , , , , , , , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
BlackWell Publishing Ltd
2015
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365683/ https://ncbi.nlm.nih.gov/pubmed/25266280 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.27539 |
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