Downregulated lincRNA HOTAIR expression in ovarian cancer stem cells decreases its tumorgeniesis and metastasis by inhibiting epithelial-mesenchymal transition

BACKGROUND: Emerging evidence indicates that dysregulated long intervening non-coding RNA (lincRNA) HOTAIR correlates highly with tumor invasion and metastasis but a link between the high expression of HOTAIR and the metastatic cascade of cancer stem cells (CSCs) needs to be further studied. The pur...

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Publicat a:Cancer Cell Int
Autors principals: Wang, Jing, Chen, Dengyu, He, Xiangfeng, Zhang, Yuxia, Shi, Fangfang, Wu, Di, Chen, Junsong, Zhang, Ying, Zhao, Fengsu, Dou, Jun
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2015
Matèries:
Primary Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365532/
https://ncbi.nlm.nih.gov/pubmed/25792974
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-015-0174-4
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