MicroRNA-200c overexpression inhibits tumorigenicity and metastasis of CD117(+)CD44(+) ovarian cancer stem cells by regulating epithelial-mesenchymal transition

BACKGROUND: Cancer stem cells (CSCs) are believed to be ‘seed cell’ in cancer recurrence and metastasis. MicroRNAs (miRNAs) can play an important role in the progression of primary tumor towards metastasis by regulating the epithelial-mesenchymal transition (EMT). The goal of this study was to inves...

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Detalhes bibliográficos
Main Authors: Chen, Dengyu, Zhang, Yunxia, Wang, Jing, Chen, Junsong, Yang, Cuiping, Cai, Kai, Wang, Xiaoying, Shi, Fangfang, Dou, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2013
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729499/
https://ncbi.nlm.nih.gov/pubmed/23842108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1757-2215-6-50
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