ICAM-5 affects spine maturation by regulation of NMDA receptor binding to α-actinin

ICAM-5 is a negative regulator of dendritic spine maturation and facilitates the formation of filopodia. Its absence results in improved memory functions, but the mechanisms have remained poorly understood. Activation of NMDA receptors induces ICAM-5 ectodomain cleavage through a matrix metalloprote...

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Bibliografische gegevens
Gepubliceerd in:Biol Open
Hoofdauteurs: Ning, Lin, Paetau, Sonja, Nyman-Huttunen, Henrietta, Tian, Li, Gahmberg, Carl G.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Company of Biologists 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365481/
https://ncbi.nlm.nih.gov/pubmed/25572420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/bio.201410439
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