Anti-allergic cromones inhibit neutrophil recruitment onto vascular endothelium via annexin-A1 mobilization

OBJECTIVES: The anti-allergic ‘mast cell stabilising’ cromones release the anti-inflammatory protein annexin A1 (Anx-A1) from U937 cells. These drugs also inhibit polymorphonuclear leukocyte (PMN) trafficking. Since PMN can synthesise and release large amounts of Anx-A1, we hypothesised that a simil...

Full description

Saved in:
Bibliographic Details
Published in:Arterioscler Thromb Vasc Biol
Main Authors: Yazid, Samia, Leoni, Giovanna, Getting, Stephen J, Cooper, Dianne, Solito, Egle, Perretti, Mauro, Flower, Roderick J
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365443/
https://ncbi.nlm.nih.gov/pubmed/20558817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.110.209536
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items