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Single cell visualization of transcription kinetics variance of highly mobile identical genes using 3D nanoimaging

Multi-cell biochemical assays and single cell fluorescence measurements revealed that the elongation rate of Polymerase II (PolII) in eukaryotes varies largely across different cell types and genes. However, there is not yet a consensus whether intrinsic factors such as the position, local mobility...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Annibale, Paolo, Gratton, Enrico
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365385/
https://ncbi.nlm.nih.gov/pubmed/25788248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09258
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