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Single cell visualization of transcription kinetics variance of highly mobile identical genes using 3D nanoimaging

Multi-cell biochemical assays and single cell fluorescence measurements revealed that the elongation rate of Polymerase II (PolII) in eukaryotes varies largely across different cell types and genes. However, there is not yet a consensus whether intrinsic factors such as the position, local mobility...

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Vydáno v:Sci Rep
Hlavní autoři: Annibale, Paolo, Gratton, Enrico
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365385/
https://ncbi.nlm.nih.gov/pubmed/25788248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09258
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