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Developing de novo human artificial chromosomes in embryonic stem cells using HSV-1 amplicon technology
De novo artificial chromosomes expressing genes have been generated in human embryonic stem cells (hESc) and are maintained following differentiation into other cell types. Human artificial chromosomes (HAC) are small, functional, extrachromosomal elements, which behave as normal chromosomes in huma...
Gespeichert in:
| Veröffentlicht in: | Chromosome Res |
|---|---|
| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Springer Netherlands
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365269/ https://ncbi.nlm.nih.gov/pubmed/25657030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10577-014-9456-2 |
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