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Developing de novo human artificial chromosomes in embryonic stem cells using HSV-1 amplicon technology
De novo artificial chromosomes expressing genes have been generated in human embryonic stem cells (hESc) and are maintained following differentiation into other cell types. Human artificial chromosomes (HAC) are small, functional, extrachromosomal elements, which behave as normal chromosomes in huma...
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| Pubblicato in: | Chromosome Res |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Springer Netherlands
2015
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4365269/ https://ncbi.nlm.nih.gov/pubmed/25657030 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10577-014-9456-2 |
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