Transport through recycling endosomes requires EHD1 recruitment by a phosphatidylserine translocase

P(4)-ATPases translocate aminophospholipids, such as phosphatidylserine (PS), to the cytosolic leaflet of membranes. PS is highly enriched in recycling endosomes (REs) and is essential for endosomal membrane traffic. Here, we show that PS flipping by an RE-localized P(4)-ATPase is required for the r...

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Veröffentlicht in:EMBO J
Hauptverfasser: Lee, Shoken, Uchida, Yasunori, Wang, Jiao, Matsudaira, Tatsuyuki, Nakagawa, Takatoshi, Kishimoto, Takuma, Mukai, Kojiro, Inaba, Takehiko, Kobayashi, Toshihide, Molday, Robert S, Taguchi, Tomohiko, Arai, Hiroyuki
Format: Artigo
Sprache:Inglês
Veröffentlicht: BlackWell Publishing Ltd 2015
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365035/
https://ncbi.nlm.nih.gov/pubmed/25595798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201489703
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