Endosomal phosphatidylserine is critical for the YAP signalling pathway in proliferating cells

Yes-associated protein (YAP) is a recently discovered growth-promoting transcription coactivator that has been shown to regulate the malignancy of various cancers. How YAP is regulated is not fully understood. Here, we show that one of the factors regulating YAP is phosphatidylserine (PS) in recycli...

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Udgivet i:Nat Commun
Main Authors: Matsudaira, Tatsuyuki, Mukai, Kojiro, Noguchi, Taishin, Hasegawa, Junya, Hatta, Tomohisa, Iemura, Shun-ichiro, Natsume, Tohru, Miyamura, Norio, Nishina, Hiroshi, Nakayama, Jun, Semba, Kentaro, Tomita, Takuya, Murata, Shigeo, Arai, Hiroyuki, Taguchi, Tomohiko
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5665887/
https://ncbi.nlm.nih.gov/pubmed/29093443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-01255-3
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