Insulin Growth Factor 1 Receptor Expression Is Associated with NOTCH1 Mutation, Trisomy 12 and Aggressive Clinical Course in Chronic Lymphocytic Leukaemia

IGF1R is emerging as an important gene in the pathogenesis of many solid and haematological cancers and its over-expression has been reported as frequently associated with aggressive disease and chemotherapy resistance. In this study we performed an investigation of the role of IGF1R expression in a...

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Détails bibliographiques
Publié dans:PLoS One
Auteurs principaux: Maura, Francesco, Mosca, Laura, Fabris, Sonia, Cutrona, Giovanna, Matis, Serena, Lionetti, Marta, Agnelli, Luca, Barbieri, Marzia, D’Anca, Marianna, Manzoni, Martina, Colombo, Monica, Massucco, Carlotta, Reverberi, Daniele, Gentile, Massimo, Recchia, Anna Grazia, Bossio, Sabrina, Ilariucci, Fiorella, Musolino, Caterina, Di Raimondo, Francesco, Cortelezzi, Agostino, Morabito, Fortunato, Ferrarini, Manlio, Neri, Antonino
Format: Artigo
Langue:Inglês
Publié: Public Library of Science 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365018/
https://ncbi.nlm.nih.gov/pubmed/25786252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118801
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