Insulin Growth Factor 1 Receptor Expression Is Associated with NOTCH1 Mutation, Trisomy 12 and Aggressive Clinical Course in Chronic Lymphocytic Leukaemia

IGF1R is emerging as an important gene in the pathogenesis of many solid and haematological cancers and its over-expression has been reported as frequently associated with aggressive disease and chemotherapy resistance. In this study we performed an investigation of the role of IGF1R expression in a...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Maura, Francesco, Mosca, Laura, Fabris, Sonia, Cutrona, Giovanna, Matis, Serena, Lionetti, Marta, Agnelli, Luca, Barbieri, Marzia, D’Anca, Marianna, Manzoni, Martina, Colombo, Monica, Massucco, Carlotta, Reverberi, Daniele, Gentile, Massimo, Recchia, Anna Grazia, Bossio, Sabrina, Ilariucci, Fiorella, Musolino, Caterina, Di Raimondo, Francesco, Cortelezzi, Agostino, Morabito, Fortunato, Ferrarini, Manlio, Neri, Antonino
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4365018/
https://ncbi.nlm.nih.gov/pubmed/25786252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118801
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