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Deletion of ERK2 Mitogen-Activated Protein Kinase Identifies Its Key Roles in Cortical Neurogenesis and Cognitive Function

The mitogen-activated protein (MAP) kinases ERK1 and ERK2 are critical intracellular signaling intermediates; however, little is known about their isoform-specific functions in vivo. We have examined the role of ERK2 in neural development by conditional inactivation of the murine mapk1/ERK2 gene in...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Samuels, Ivy S., Karlo, J. Colleen, Faruzzi, Alicia N., Pickering, Kathryn, Herrup, Karl, Sweatt, J. David, Saitta, Sulagna C., Landreth, Gary E.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2008
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Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364995/
https://ncbi.nlm.nih.gov/pubmed/18596172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0679-08.2008
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