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Ruta graveolens L. Induces Death of Glioblastoma Cells and Neural Progenitors, but Not of Neurons, via ERK 1/2 and AKT Activation

Glioblastoma multiforme is a highly aggressive brain tumor whose prognosis is very poor. Due to early invasion of brain parenchyma, its complete surgical removal is nearly impossible, and even after aggressive combined treatment (association of surgery and chemo- and radio-therapy) five-year surviva...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Gentile, Maria Teresa, Ciniglia, Claudia, Reccia, Mafalda G., Volpicelli, Floriana, Gatti, Monica, Thellung, Stefano, Florio, Tullio, Melone, Mariarosa A. B., Colucci-D’Amato, Luca
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364962/
https://ncbi.nlm.nih.gov/pubmed/25785932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118864
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