Ruta graveolens L. Induces Death of Glioblastoma Cells and Neural Progenitors, but Not of Neurons, via ERK 1/2 and AKT Activation

Glioblastoma multiforme is a highly aggressive brain tumor whose prognosis is very poor. Due to early invasion of brain parenchyma, its complete surgical removal is nearly impossible, and even after aggressive combined treatment (association of surgery and chemo- and radio-therapy) five-year surviva...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Gentile, Maria Teresa, Ciniglia, Claudia, Reccia, Mafalda G., Volpicelli, Floriana, Gatti, Monica, Thellung, Stefano, Florio, Tullio, Melone, Mariarosa A. B., Colucci-D’Amato, Luca
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364962/
https://ncbi.nlm.nih.gov/pubmed/25785932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118864
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