Zeb1 affects epithelial cell adhesion by diverting glycosphingolipid metabolism

This study proposes that the transcription factor Zeb1 modulates epithelial cell adhesion by diverting glycosphingolipid metabolism. Zeb1 promotes expression of a-series glycosphingolipids via regulating expression of GM3 synthase (St3gal5), which mechanistically involves Zeb1 binding to the St3gal5...

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Bibliografische gegevens
Gepubliceerd in:EMBO Rep
Hoofdauteurs: Mathow, Daniel, Chessa, Federica, Rabionet, Mariona, Kaden, Sylvia, Jennemann, Richard, Sandhoff, Roger, Gröne, Hermann-Josef, Feuerborn, Alexander
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: BlackWell Publishing Ltd 2015
Onderwerpen:
Scientific Reports
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364871/
https://ncbi.nlm.nih.gov/pubmed/25643708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201439333
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