In Vitro Matured Oocytes Are More Susceptible than In Vivo Matured Oocytes to Mock ICSI Induced Functional and Genetic Changes

BACKGROUND: Concerns regarding the safety of ICSI have been intensified recently due to increased risk of birth defects in ICSI born children. Although fertilization rate is significantly higher in ICSI cycles, studies have failed to demonstrate the benefits of ICSI in improving the pregnancy rate....

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Veröffentlicht in:PLoS One
Hauptverfasser: Uppangala, Shubhashree, Dhiman, Shilly, Salian, Sujit Raj, Singh, Vikram Jeet, Kalthur, Guruprasad, Adiga, Satish Kumar
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364773/
https://ncbi.nlm.nih.gov/pubmed/25786120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119735
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