Early prepubertal cyclophosphamide exposure in mice results in long-term loss of ovarian reserve, and impaired embryonic development and blastocyst quality

BACKGROUND: Due to improved treatment, there is an increasing focus on the reproductive potential of survivors of childhood cancer. Cytotoxic chemotherapy accelerates the decline in the number of primordial follicles within the mammalian ovary at all ages, but effects on the developmental potential...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:PLoS One
Egile Nagusiak: Salian, Sujith Raj, Uppangala, Shubhashree, Cheredath, Aswathi, D’Souza, Fiona, Kalthur, Guruprasad, Nayak, Vinod C., Anderson, Richard A., Adiga, Satish Kumar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2020
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7310698/
https://ncbi.nlm.nih.gov/pubmed/32574203
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0235140
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