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Pharmaceutical and pharmacokinetic characterization of a novel sublingual buprenorphine/naloxone tablet formulation in healthy volunteers

CONTEXT: Bitter taste, as well as dissolve time, presents a significant challenge for the acceptability of formulations for oral transmucosal drug delivery. OBJECTIVE: To characterize a novel sublingual tablet formulation of buprenorphine/naloxone with regards to pharmacokinetics, dissolve time and...

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Bibliografische gegevens
Gepubliceerd in:Drug Dev Ind Pharm
Hoofdauteurs: Fischer, Andreas, Jönsson, Martin, Hjelmström, Peter
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364559/
https://ncbi.nlm.nih.gov/pubmed/24099551
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3109/03639045.2013.846365
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