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Effect of Telaprevir on the Pharmacokinetics of Buprenorphine in Volunteers on Stable Buprenorphine/Naloxone Maintenance Therapy

This was an open-label, single-sequence trial in hepatitis C virus-negative volunteers on stable, individualized, buprenorphine maintenance therapy. Telaprevir at 750 mg every 8 h was coadministered with buprenorphine/naloxone (4:1 ratio as sublingual tablets) for 7 days with food. Pharmacokinetic p...

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Bibliografski detalji
Glavni autori: Luo, Xia, Trevejo, Jose, van Heeswijk, Rolf P. G., Smith, Frances, Garg, Varun
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3393419/
https://ncbi.nlm.nih.gov/pubmed/22564847
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00077-12
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