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Docosahexaenoic Acid Supplementation Alters Key Properties of Cardiac Mitochondria and Modestly Attenuates Development of Left Ventricular Dysfunction in Pressure Overload-Induced Heart Failure

PURPOSE: Supplementation with the n3 polyunsaturated fatty acid docosahexaenoic acid (DHA) is beneficial in heart failure patients, however the mechanisms are unclear. DHA is incorporated into membrane phospholipids, which may prevent mitochondrial dysfunction. Thus we assessed the effects of DHA su...

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Publicat a:Cardiovasc Drugs Ther
Autors principals: Dabkowski, Erinne R., O’Connell, Kelly A., Xu, Wenhong, Ribeiro, Rogerio F., Hecker, Peter A., Shekar, Kadambari Chandra, Stanley, William C., Daneault, Caroline, Rosiers, Christine Des
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364545/
https://ncbi.nlm.nih.gov/pubmed/24013804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-013-6487-4
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