Docosahexaenoic Acid Supplementation Alters Key Properties of Cardiac Mitochondria and Modestly Attenuates Development of Left Ventricular Dysfunction in Pressure Overload-Induced Heart Failure

PURPOSE: Supplementation with the n3 polyunsaturated fatty acid docosahexaenoic acid (DHA) is beneficial in heart failure patients, however the mechanisms are unclear. DHA is incorporated into membrane phospholipids, which may prevent mitochondrial dysfunction. Thus we assessed the effects of DHA su...

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Pubblicato in:Cardiovasc Drugs Ther
Autori principali: Dabkowski, Erinne R., O’Connell, Kelly A., Xu, Wenhong, Ribeiro, Rogerio F., Hecker, Peter A., Shekar, Kadambari Chandra, Stanley, William C., Daneault, Caroline, Rosiers, Christine Des
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364545/
https://ncbi.nlm.nih.gov/pubmed/24013804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10557-013-6487-4
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