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A Response Regulator from a Soil Metagenome Enhances Resistance to the β-Lactam Antibiotic Carbenicillin in Escherichia coli

Functional metagenomic analysis of soil metagenomes is a method for uncovering as-yet unidentified mechanisms for antibiotic resistance. Here we report an unconventional mode by which a response regulator derived from a soil metagenome confers resistance to the β-lactam antibiotic carbenicillin in E...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Allen, Heather K., An, Ran, Handelsman, Jo, Moe, Luke A.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364456/
https://ncbi.nlm.nih.gov/pubmed/25782011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120094
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