Novel Metagenome-Derived Carboxylesterase That Hydrolyzes β-Lactam Antibiotics

It has been proposed that family VIII carboxylesterases and class C β-lactamases are phylogenetically related; however, none of carboxylesterases has been reported to hydrolyze β-lactam antibiotics except nitrocefin, a nonclinical chromogenic substrate. Here, we describe the first example of a novel...

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Detalhes bibliográficos
Main Authors: Jeon, Jeong Ho, Kim, Soo-Jin, Lee, Hyun Sook, Cha, Sun-Shin, Lee, Jung Hun, Yoon, Sang-Hong, Koo, Bon-Sung, Lee, Chang-Muk, Choi, Sang Ho, Lee, Sang Hee, Kang, Sung Gyun, Lee, Jung-Hyun
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2011
Assuntos:
Environmental Microbiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3209169/
https://ncbi.nlm.nih.gov/pubmed/21908637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.05363-11
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