Adoptive transfer of human gingiva-derived mesenchymal stem cells ameliorates collagen-induced arthritis via suppressing Th1 and Th17 and enhancing regulatory T cell differentiation

OBJECTIVE: Current approaches offer no cures for rheumatoid arthritis (RA). Accumulating evidence has revealed that manipulation of bone-marrow mesenchymal stem cells (BMSCs) may have the potential to treat RA. While BMSC-based therapy faces many challenges such as limited cell availability and redu...

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Veröffentlicht in:Arthritis Rheum
Hauptverfasser: Chen, Maogen, Su, Wenru, Lin, Xiaohong, Guo, Zhiyong, Wang, Julie, Zhang, Qunzhou, Brand, David, Ryffel, Bernhard, Huang, Jiefu, Liu, Zhongmin, He, Xiaoshun, Le, Anh D., Zheng, Song Guo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364405/
https://ncbi.nlm.nih.gov/pubmed/23400582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.37894
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