Mutations in early follicular lymphoma progenitors are associated with suppressed antigen presentation

Follicular lymphoma (FL) is incurable with conventional therapies and has a clinical course typified by multiple relapses after therapy. These tumors are genetically characterized by B-cell leukemia/lymphoma 2 (BCL2) translocation and mutation of genes involved in chromatin modification. By analyzin...

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Udgivet i:Proc Natl Acad Sci U S A
Main Authors: Green, Michael R., Kihira, Shingo, Liu, Chih Long, Nair, Ramesh V., Salari, Raheleh, Gentles, Andrew J., Irish, Jonathan, Stehr, Henning, Vicente-Dueñas, Carolina, Romero-Camarero, Isabel, Sanchez-Garcia, Isidro, Plevritis, Sylvia K., Arber, Daniel A., Batzoglou, Serafim, Levy, Ronald, Alizadeh, Ash A.
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2015
Fag:
PNAS Plus
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364211/
https://ncbi.nlm.nih.gov/pubmed/25713363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1501199112
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