A pluripotency signature predicts histologic transformation and influences survival in follicular lymphoma patients

Histologic transformation (HT) of follicular lymphoma to diffuse large B-cell lymphoma (DLBCL-t) is associated with accelerated disease course and drastically worse outcome, yet the underlying mechanisms are poorly understood. We show that a network of gene transcriptional modules underlies HT. Cent...

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Detalhes bibliográficos
Main Authors: Gentles, Andrew J., Alizadeh, Ash A., Lee, Su-In, Myklebust, June H., Shachaf, Catherine M., Shahbaba, Babak, Levy, Ronald, Koller, Daphne, Plevritis, Sylvia K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2009
Assuntos:
Clinical Trials and Observations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2759646/
https://ncbi.nlm.nih.gov/pubmed/19636063
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2009-02-202465
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