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Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer
BACKGROUND: Survivin is a protein that is normally present only in G2 and M-phases in somatic cells, however, in cancer cells, it is expressed throughout the cell cycle. A prosurvival factor, survivin is both an inhibitor of apoptosis and an essential mitotic protein, thus it has attracted much atte...
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| Publicat a: | Cancer Cell Int |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2014
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364043/ https://ncbi.nlm.nih.gov/pubmed/25788861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0078-8 |
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