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Analysis of the functional repertoire of a mutant form of survivin, K129E, which has been linked to lung cancer

BACKGROUND: Survivin is a protein that is normally present only in G2 and M-phases in somatic cells, however, in cancer cells, it is expressed throughout the cell cycle. A prosurvival factor, survivin is both an inhibitor of apoptosis and an essential mitotic protein, thus it has attracted much atte...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Aljaberi, Aysha M, Webster, Jamie RM, Wheatley, Sally P
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364043/
https://ncbi.nlm.nih.gov/pubmed/25788861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-014-0078-8
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