Functional Analysis of Sirtuin Genes in Multiple Plasmodium falciparum Strains

Plasmodium falciparum, the causative agent of severe human malaria, employs antigenic variation to avoid host immunity. Antigenic variation is achieved by transcriptional switching amongst polymorphic var genes, enforced by epigenetic modification of chromatin. The histone-modifying ‘sirtuin’ enzyme...

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Bibliografski detalji
Izdano u:PLoS One
Glavni autori: Merrick, Catherine J., Jiang, Rays H. Y., Skillman, Kristen M., Samarakoon, Upeka, Moore, Rachel M., Dzikowski, Ron, Ferdig, Michael T., Duraisingh, Manoj T.
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2015
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364008/
https://ncbi.nlm.nih.gov/pubmed/25780929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118865
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