Functional Analysis of Sirtuin Genes in Multiple Plasmodium falciparum Strains

Plasmodium falciparum, the causative agent of severe human malaria, employs antigenic variation to avoid host immunity. Antigenic variation is achieved by transcriptional switching amongst polymorphic var genes, enforced by epigenetic modification of chromatin. The histone-modifying ‘sirtuin’ enzyme...

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Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Merrick, Catherine J., Jiang, Rays H. Y., Skillman, Kristen M., Samarakoon, Upeka, Moore, Rachel M., Dzikowski, Ron, Ferdig, Michael T., Duraisingh, Manoj T.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4364008/
https://ncbi.nlm.nih.gov/pubmed/25780929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118865
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