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Functional Analysis of Sirtuin Genes in Multiple Plasmodium falciparum Strains
Plasmodium falciparum, the causative agent of severe human malaria, employs antigenic variation to avoid host immunity. Antigenic variation is achieved by transcriptional switching amongst polymorphic var genes, enforced by epigenetic modification of chromatin. The histone-modifying ‘sirtuin’ enzyme...
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| Publicado no: | PLoS One |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4364008/ https://ncbi.nlm.nih.gov/pubmed/25780929 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0118865 |
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