Pegasus: a comprehensive annotation and prediction tool for detection of driver gene fusions in cancer

BACKGROUND: The extraordinary success of imatinib in the treatment of BCR-ABL1 associated cancers underscores the need to identify novel functional gene fusions in cancer. RNA sequencing offers a genome-wide view of expressed transcripts, uncovering biologically functional gene fusions. Although sev...

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Foilsithe in:BMC Syst Biol
Main Authors: Abate, Francesco, Zairis, Sakellarios, Ficarra, Elisa, Acquaviva, Andrea, Wiggins, Chris H, Frattini, Veronique, Lasorella, Anna, Iavarone, Antonio, Inghirami, Giorgio, Rabadan, Raul
Formáid: Artigo
Teanga:Inglês
Foilsithe: BioMed Central 2014
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363948/
https://ncbi.nlm.nih.gov/pubmed/25183062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12918-014-0097-z
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