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Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse

Despite the advent of oral phosphodiesterase-5 inhibitors, curative treatment for erectile dysfunction (ED) remains unavailable. Recently, the link between ED and cardiovascular disease was unveiled and the main etiology of ED was found to be vasculogenic. Therefore, neovascularization is a promisin...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ryu, Ji-Kan, Kim, Woo Jean, Koh, Young Jun, Piao, Shuguang, Jin, Hai-Rong, Lee, Sae-Won, Choi, Min Ji, Shin, Hwa-Yean, Kwon, Mi-Hye, Jung, Keehoon, Koh, Gou Young, Suh, Jun-Kyu
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363832/
https://ncbi.nlm.nih.gov/pubmed/25783805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09222
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