Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse

Despite the advent of oral phosphodiesterase-5 inhibitors, curative treatment for erectile dysfunction (ED) remains unavailable. Recently, the link between ED and cardiovascular disease was unveiled and the main etiology of ED was found to be vasculogenic. Therefore, neovascularization is a promisin...

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Vydáno v:Sci Rep
Hlavní autoři: Ryu, Ji-Kan, Kim, Woo Jean, Koh, Young Jun, Piao, Shuguang, Jin, Hai-Rong, Lee, Sae-Won, Choi, Min Ji, Shin, Hwa-Yean, Kwon, Mi-Hye, Jung, Keehoon, Koh, Gou Young, Suh, Jun-Kyu
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363832/
https://ncbi.nlm.nih.gov/pubmed/25783805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09222
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