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Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse

Despite the advent of oral phosphodiesterase-5 inhibitors, curative treatment for erectile dysfunction (ED) remains unavailable. Recently, the link between ED and cardiovascular disease was unveiled and the main etiology of ED was found to be vasculogenic. Therefore, neovascularization is a promisin...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ryu, Ji-Kan, Kim, Woo Jean, Koh, Young Jun, Piao, Shuguang, Jin, Hai-Rong, Lee, Sae-Won, Choi, Min Ji, Shin, Hwa-Yean, Kwon, Mi-Hye, Jung, Keehoon, Koh, Gou Young, Suh, Jun-Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363832/
https://ncbi.nlm.nih.gov/pubmed/25783805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09222
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