Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse

Despite the advent of oral phosphodiesterase-5 inhibitors, curative treatment for erectile dysfunction (ED) remains unavailable. Recently, the link between ED and cardiovascular disease was unveiled and the main etiology of ED was found to be vasculogenic. Therefore, neovascularization is a promisin...

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Pubblicato in:Sci Rep
Autori principali: Ryu, Ji-Kan, Kim, Woo Jean, Koh, Young Jun, Piao, Shuguang, Jin, Hai-Rong, Lee, Sae-Won, Choi, Min Ji, Shin, Hwa-Yean, Kwon, Mi-Hye, Jung, Keehoon, Koh, Gou Young, Suh, Jun-Kyu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363832/
https://ncbi.nlm.nih.gov/pubmed/25783805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep09222
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