Intracavernous Delivery of a Designed Angiopoietin-1 Variant Rescues Erectile Function by Enhancing Endothelial Regeneration in the Streptozotocin-Induced Diabetic Mouse

OBJECTIVE: Patients with diabetic erectile dysfunction often have severe endothelial dysfunction and respond poorly to oral phosphodiesterase-5 inhibitors. We examined the effectiveness of the potent angiopoietin-1 (Ang1) variant, cartilage oligomeric matrix protein (COMP)-Ang1, in promoting caverno...

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Main Authors: Jin, Hai-Rong, Kim, Woo Jean, Song, Jae Sook, Piao, Shuguang, Choi, Min Ji, Tumurbaatar, Munkhbayar, Shin, Sun Hwa, Yin, Guo Nan, Koh, Gou Young, Ryu, Ji-Kan, Suh, Jun-Kyu
Format: Artigo
Jezik:Inglês
Izdano: American Diabetes Association 2011
Teme:
Complications
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3046858/
https://ncbi.nlm.nih.gov/pubmed/21270241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0354
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