Reassessment of HIV-1 Acute Phase Infectivity: Accounting for Heterogeneity and Study Design with Simulated Cohorts

BACKGROUND: The infectivity of the HIV-1 acute phase has been directly measured only once, from a retrospectively identified cohort of serodiscordant heterosexual couples in Rakai, Uganda. Analyses of this cohort underlie the widespread view that the acute phase is highly infectious, even more so th...

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Veröffentlicht in:PLoS Med
Hauptverfasser: Bellan, Steve E., Dushoff, Jonathan, Galvani, Alison P., Meyers, Lauren Ancel
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363602/
https://ncbi.nlm.nih.gov/pubmed/25781323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pmed.1001801
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