Identification and Characterization of Clostridium perfringens Beta Toxin Variants with Differing Trypsin Sensitivity and In Vitro Cytotoxicity Activity

By producing toxins, Clostridium perfringens causes devastating diseases of both humans and animals. C. perfringens beta toxin (CPB) is the major virulence determinant for type C infections and is also implicated in type B infections, but little is known about the CPB structure-function relationship...

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Detalles Bibliográficos
Publicado en:Infect Immun
Autores principales: Theoret, James R., Uzal, Francisco A., McClane, Bruce A.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2015
Materias:
Molecular Pathogenesis
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363432/
https://ncbi.nlm.nih.gov/pubmed/25643999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02864-14
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