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Toll-Like Receptor 2 (TLR2) and TLR9 Play Opposing Roles in Host Innate Immunity against Salmonella enterica Serovar Typhimurium Infection

Toll-like receptors (TLRs) are evolutionarily conserved host proteins that are essential for effective host defense against pathogens. However, recent studies suggest that some TLRs can negatively regulate immune responses. We observed here that TLR2 and TLR9 played opposite roles in regulating inna...

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Detalhes bibliográficos
Publicado no:Infect Immun
Main Authors: Zhan, Renhui, Han, Qiuju, Zhang, Cai, Tian, Zhigang, Zhang, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363406/
https://ncbi.nlm.nih.gov/pubmed/25667264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02870-14
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