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Toll-Like Receptor 2 (TLR2) and TLR9 Play Opposing Roles in Host Innate Immunity against Salmonella enterica Serovar Typhimurium Infection

Toll-like receptors (TLRs) are evolutionarily conserved host proteins that are essential for effective host defense against pathogens. However, recent studies suggest that some TLRs can negatively regulate immune responses. We observed here that TLR2 and TLR9 played opposite roles in regulating inna...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Main Authors: Zhan, Renhui, Han, Qiuju, Zhang, Cai, Tian, Zhigang, Zhang, Jian
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363406/
https://ncbi.nlm.nih.gov/pubmed/25667264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02870-14
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