The Innate Immune Response to Salmonella enterica Serovar Typhimurium by Macrophages Is Dependent on TREM2-DAP12

Macrophage recognition of Salmonella enterica serovar Typhimurium leads to a cascade of signaling events, including the activation of Src family and Syk kinases and the production of reactive oxygen species (ROS), which are critical for host innate defense during early stages of bacterial infection....

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Detalhes bibliográficos
Main Authors: Charles, Julia F., Humphrey, Mary Beth, Zhao, Xiaodan, Quarles, Ellen, Nakamura, Mary C., Aderem, Alan, Seaman, William E., Smith, Kelly D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Host Response and Inflammation
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2423085/
https://ncbi.nlm.nih.gov/pubmed/18391000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.00115-08
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