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Characterization of a novel domain ‘GATE’ in the ABC protein DrrA and its role in drug efflux by the DrrAB complex

A novel domain, GATE (Glycine-loop And Transducer Element), is identified in the ABC protein DrrA. This domain shows sequence and structural conservation among close homologs of DrrA as well as distantly-related ABC proteins. Among the highly conserved residues in this domain are three glycines, G21...

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Publié dans:Biochem Biophys Res Commun
Auteurs principaux: Zhang, Han, Rahman, Sadia, Li, Wen, Fu, Guoxing, Kaur, Parjit
Format: Artigo
Langue:Inglês
Publié: 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363271/
https://ncbi.nlm.nih.gov/pubmed/25721665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2015.02.086
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