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A simple data-adaptive probabilistic variant calling model
BACKGROUND: Several sources of noise obfuscate the identification of single nucleotide variation (SNV) in next generation sequencing data. For instance, errors may be introduced during library construction and sequencing steps. In addition, the reference genome and the algorithms used for the alignm...
Guardat en:
| Publicat a: | Algorithms Mol Biol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
BioMed Central
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363181/ https://ncbi.nlm.nih.gov/pubmed/25788974 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13015-015-0037-5 |
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