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Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons

Neuropeptide Y (NPY) is present in the superficial laminae of the dorsal horn and inhibits spinal nociceptive processing, but the mechanisms underlying its anti-hyperalgesic actions are unclear. We hypothesized that NPY acts at neuropeptide Y1 receptors in dorsal horn to decrease nociception by inhi...

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發表在:Neuroscience
Main Authors: Taylor, Bradley K., Fu, Weisi, Kuphal, Karen E., Stiller, Carl-Olav, Winter, Michelle K., Chen, Wenling, Corder, Gregory F., Urban, Janice H., McCarson, Kenneth E., Marvizon, Juan Carlos
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363128/
https://ncbi.nlm.nih.gov/pubmed/24184981
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.10.054
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