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Inflammation enhances Y1 receptor signaling, neuropeptide Y-mediated inhibition of hyperalgesia, and substance P release from primary afferent neurons
Neuropeptide Y (NPY) is present in the superficial laminae of the dorsal horn and inhibits spinal nociceptive processing, but the mechanisms underlying its anti-hyperalgesic actions are unclear. We hypothesized that NPY acts at neuropeptide Y1 receptors in dorsal horn to decrease nociception by inhi...
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發表在: | Neuroscience |
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Main Authors: | , , , , , , , , , |
格式: | Artigo |
語言: | Inglês |
出版: |
2013
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主題: | |
在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363128/ https://ncbi.nlm.nih.gov/pubmed/24184981 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2013.10.054 |
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