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Radiation persistently promoted oxidative stress, activated mTOR via PI3K/Akt, and downregulated autophagy pathway in mouse intestine

While acute effects of toxic radiation doses on intestine are well established, we are yet to acquire a complete spectrum of sub-lethal radiation-induced chronic intestinal perturbations at the molecular level. We investigated persistent effects of a radiation dose (2 Gy) commonly used as a daily fr...

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Detalhes bibliográficos
Publicado no:Int J Biochem Cell Biol
Main Authors: Datta, Kamal, Suman, Shubhankar, Fornace, Albert J
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4363107/
https://ncbi.nlm.nih.gov/pubmed/25449263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biocel.2014.10.022
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