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HIV-1 ssRNA induces CXCL13 secretion in human monocytes via TLR7 activation and plasmacytoid dendritic cell-derived type I IFN
Elevated levels of the chemokine, CXCL13, have been observed in the plasma of chronic HIV-1 infected subjects and have been correlated with plasma viremia, which in turn has been linked to progressive dysregulation of humoral responses. In this study we sought to identify mechanisms of CXCL13 induct...
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Pubblicato in: | J Immunol |
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Autori principali: | , , , , |
Natura: | Artigo |
Lingua: | Inglês |
Pubblicazione: |
2015
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Soggetti: | |
Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4363079/ https://ncbi.nlm.nih.gov/pubmed/25667414 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1400952 |
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