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Activity-dependent degeneration of axotomized neuromuscular synapses in Wld(S) mice

Activity and disuse of synapses are thought to influence progression of several neurodegenerative diseases in which synaptic degeneration is an early sign. Here we tested whether stimulation or disuse renders neuromuscular synapses more or less vulnerable to degeneration, using axotomy as a robust t...

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Bibliografiske detaljer
Udgivet i:Neuroscience
Main Authors: Brown, R., Hynes-Allen, A., Swan, A.J., Dissanayake, K.N., Gillingwater, T.H., Ribchester, R.R.
Format: Artigo
Sprog:Inglês
Udgivet: Elsevier Science 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362769/
https://ncbi.nlm.nih.gov/pubmed/25617654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2015.01.018
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