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Highly specific role of the insulin receptor in breast cancer progression

Accumulating evidence from clinical trials indicates that specific targeting of the IGF1 receptor (IGF1R) is not efficient as an anti-breast cancer treatment. One possible reason is that the mitogenic signals from the insulin receptor (IR) can be processed independently or as compensation to inhibit...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Endocr Relat Cancer
Hauptverfasser: Rostoker, Ran, Abelson, Sagi, Bitton-Worms, Keren, Genkin, Inna, Ben-Shmuel, Sarit, Dakwar, Maria, Orr, Zila Shen, Caspi, Avishay, Tzukerman, Maty, LeRoith, Derek
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362669/
https://ncbi.nlm.nih.gov/pubmed/25694511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1530/ERC-14-0490
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