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Injury-stimulated Hedgehog signaling promotes regenerative proliferation of Drosophila intestinal stem cells

Many adult tissues are maintained by resident stem cells that elevate their proliferation in response to injury. The regulatory mechanisms underlying regenerative proliferation are still poorly understood. Here we show that injury induces Hedgehog (Hh) signaling in enteroblasts (EBs) to promote inte...

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Podrobná bibliografie
Vydáno v:J Cell Biol
Hlavní autoři: Tian, Aiguo, Shi, Qing, Jiang, Alice, Li, Shuangxi, Wang, Bing, Jiang, Jin
Médium: Artigo
Jazyk:Inglês
Vydáno: The Rockefeller University Press 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362464/
https://ncbi.nlm.nih.gov/pubmed/25753035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409025
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