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Injury-stimulated Hedgehog signaling promotes regenerative proliferation of Drosophila intestinal stem cells

Many adult tissues are maintained by resident stem cells that elevate their proliferation in response to injury. The regulatory mechanisms underlying regenerative proliferation are still poorly understood. Here we show that injury induces Hedgehog (Hh) signaling in enteroblasts (EBs) to promote inte...

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Bibliografiske detaljer
Udgivet i:J Cell Biol
Main Authors: Tian, Aiguo, Shi, Qing, Jiang, Alice, Li, Shuangxi, Wang, Bing, Jiang, Jin
Format: Artigo
Sprog:Inglês
Udgivet: The Rockefeller University Press 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362464/
https://ncbi.nlm.nih.gov/pubmed/25753035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409025
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