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Injury-stimulated Hedgehog signaling promotes regenerative proliferation of Drosophila intestinal stem cells

Many adult tissues are maintained by resident stem cells that elevate their proliferation in response to injury. The regulatory mechanisms underlying regenerative proliferation are still poorly understood. Here we show that injury induces Hedgehog (Hh) signaling in enteroblasts (EBs) to promote inte...

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Detalhes bibliográficos
Publicado no:J Cell Biol
Main Authors: Tian, Aiguo, Shi, Qing, Jiang, Alice, Li, Shuangxi, Wang, Bing, Jiang, Jin
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4362464/
https://ncbi.nlm.nih.gov/pubmed/25753035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201409025
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