Tax protein of human T-cell leukemia virus type I binds to the ankyrin motifs of inhibitory factor kappa B and induces nuclear translocation of transcription factor NF-kappa B proteins for transcriptional activation.

Human T-cell leukemia virus type I causes adult T-cell leukemia and tropical spastic paraparesis, and its regulator protein Tax has been implicated in the pathogenic activity of human T-cell leukemia virus type I. Tax activates transcription of viral and cellular genes through specific enhancers: th...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Hirai, H, Suzuki, T, Fujisawa, J, Inoue, J, Yoshida, M
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43624/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8170951/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.9.3584
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